If you're on a GLP-1 weight-loss medication — semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound) — Radical Fat Loss has a dedicated on-medication mode. The risk on these drugs flips to under-eating and losing muscle, so the app guards your protein and protects the lean mass you'd otherwise lose — never nagging you to eat less.
Most fat-loss apps assume the hard part is restraint — so they count, cap, and nudge you to eat less.
Appetite drops sharply. Now the danger is under-eating — too few calories, too little protein, and muscle quietly going with the fat.
About 25–38% of the weight lost on a GLP-1 is lean mass — but the fat-to-lean ratio is similar to losing the same weight by diet alone, and muscle quality generally improves. So these medications are not "muscle-wasting." The actionable concern is the absolute amount of muscle you'd lose without two simple defences: enough protein, and a little resistance training.
That combination is the most evidence-backed lever there is — resistance training prevents roughly 93.5% of the lean mass you'd otherwise lose in a deficit. The catch on a GLP-1 is that appetite suppression cuts your intake of every macro, protein included — so protein defence matters more, not less. See the graded evidence →
Radical Fat Loss is an informational, self-tracking tool — not a medication, not a diagnosis, and not a substitute for your prescriber. Your GLP-1 treatment, dose and titration are between you and your clinician.
Tell your doctor what targets the app suggests so they can sanity-check them for you, and seek care for dizziness, chest pain, fainting, or any thoughts of disordered eating.
Switch it on and the whole system inverts — from "can I eat this?" to "have I eaten enough, and enough protein?"
Instead of a ceiling, a floor. The app watches for under-eating and prompts you toward enough fuel — never toward less.
With appetite low, protein is the first thing to slip. It stays front-and-centre, with gentle reminders when you're falling short of your floor.
Prompts to keep up gentle strength work (no training to failure) so the scale moving down means fat, not muscle.
As the medication quiets the constant background chatter about food, the app tracks that trend with a validated food-noise check — so you can see it change.
Appetite and intake shift as your dose changes. Targets account for where you are, rather than assuming a fixed plan.
If you come off the medication, the plan shifts to hard-protect lean mass — because regain tends to bring back fat faster than muscle.
When people stop a GLP-1, weight tends to return — and it doesn't come back the way it left. Fat returns faster and more completely than lean (researchers call it "collateral fattening" or catch-up fat). Repeated over enough cycles, that can tilt body composition toward more fat and less muscle.
So the moment you taper or stop is exactly when protein and resistance training matter most. Rather than treating discontinuation as "done," the app treats it as its own phase — one that prioritises holding onto muscle while your appetite recovers. The references are here →
Radical Fat Loss is pre-launch. Join the early list to be first in — one email at launch, nothing before.
Join the early list